Research papers: (*corresponding author)
        • 1. S Chan, ME Fowlkes, MS Bradley, H Lee, GJ Strewler, RA Nissenson. Cloning and characterization of the mouse Gsa promoter: activation by retinoic acid in F9 teratocarcinoma cells. Endocrine Journal 2:311-316, 1994. (1.997, 93/128, 2014)
        • 2. G D’Angelo, H Lee, RI Weiner. cAMP-dependent protein kinase inhibits the mitogenic action of VEGF and FGF in capillary endothelial cells by blocking Raf activation. J. of Cellular Biochemistry 67:353-366, 1997. (3.263, 107/289, 2014)
        • 3. H Lee, C Clapp, RI Weiner. Inhibition of urokinase activity by the antiangiogenic factor 16K PRL: activation of plasminogen activator inhibitor 1 expression. Endocrinology 139:3696-3703, 1998. (4.503, 28/128, 2014)
        • 4. S An, EJ Goetzl, H Lee. Signaling mechanisms and molecular characteristics of G protein-coupled receptors for lysophosphatidic acid and sphingosine 1-phosphate J. of Cellular Biochemistry Supplements 30/31: 147-157, 1998. (3.263, 107/289, 2014)
        • 5. I Struman, F Bentzien, H Lee, V Minfroid, G D’Angelo, V Goffin, RI Weiner, J Martial. The human prolactin/growth hormone family: a new concept for regulation of angiogenesis. Proceedings of the National Academy of Sciences of the United States of America, 96:1246-1251, 1999. (9.674, 4/56, 2014)
        • 6. H Lee, EJ Geotzl, S An. Lysophosphatidic acid and sphingosine 1-phosphate stimulate endothelial cell wound healing, American J. of Physiology. 47:C612-C617, 2000. (3.785, 18/83, 2014)
        • 7. EJ Goetzl, H Lee, H Dolezalova, JS Karliner. Cellular presentation, direct effects and amplification mechanisms of lysolipid phosphates. Ann. N.Y. Acad. Sci., 905:177-187, 2000. (4.383, 6/56, 2014)
        • 8. EJ Goetzl, H Lee, T Azuma, TP Stossel, CW Turck, JS Karliner.  Gelsolin binding and cellular presentation of lysophosphatidic acid. J. Biol. Chem, 275:14573-14578, 2000. (4.573, 61/289, 2014)
        • 9. JK Voice, G Dorsam, H Lee, Y Kong, EJ Goetzl. Allergic diathesis in transgenic mice with constitutive T cell expression of inducible vasoactive intestinal peptide receptor.  FASEB J, 15:2489-96, 2001. (5.043, 9/85, 2014)
        • 10. H Lee*, JJ Liao, M Graeler, MC Huang, EJ Goetzl.  Lysophospholipid regulation of mononuclear phagocytes. BBA, 1582:175-177, 2002. (5.162, 47/289, 2014)
        • 11. MC Huang, H Lee, CC Yeh, Y Kong, CJ Zaloudek, EJ Goetzl.  Induction of protein growth factor systems in the ovaries of transgenic mice overexpressing human type 2 lysophosphatidic acid G protein-coupled receptor (LPA2). Oncogene, 23:122-129, 2004. (8.459, 13/211, 2014)
        • 12. H Lee*. Enhancement of human endothelial cell adhesion to type-I collagen by lysophosphatidic acid and sphingosine 1-phosphate. Taiwania, 49(2): 67-79, 2004.
        • 13. H Lee*, CI Lin, JJ Liao, YW Lee, HY Yang, CY Lee, HY Hsu, HL Wu. Lysophospholipids increase ICAM-1 expression in human umbilical cord vein endothelial cells through a Gi- and NFkB-dependent mechanism. American J. of Physiology, 287:C1657-C1666, 2004. (3.785, 18/83, 2014)
        • 14. SC Chuang, H Lee, JH Chen. Diurnal rhythm and temperature effect on oxygen consumption in earthworms, Amynthas gracilis and Pontoscolex corethrurus. J Exp Zool, 301(A): 737-744. 2004. (2.311, 23/153, 2014)
        • 15. YW Huang, WS Lee, GP Chang-Chien, CI Lin, CY Kao, H Lee*. Establishment of cellular detection systems for dioxin-like compounds. Chinese Bioscience, 47 (1): 1-18, 2004
        • 16. WM Hsu, FJ Hsieh, YM Jen, ML Kuo, PN Tsao, H Lee, MT Lin, HS Lai, CN Chen, DM Lai and WJ Chen. GRP78 expression correlates with histologic differentiation and favorable prognosis in neuroblastoma. Int J Cancer, 113(6):920-927. 2005. (5.085, 31/211, 2014)
        • 17. WM Hsu, FJ Hsieh, YM Jeng, ML Kuo, CN Chen, DM Lai, LJ Hsieh, BT Wang, PN Tsao, H Lee, MT Lin, HS Lai, WJ Chen. Calreticulin expression in neuroblastoma--a novel independent prognostic factor. Ann Oncol. 16(2):314-21. 2005. (7.040, 18/211, 2014)
        • 18. JJ Liao, YT Huang, H Lee*. Inhibitory effects of sphingosine 1-phosphate on proliferation of PC-3 human prostate cancer cell. Zoological Studies, 44(2): 219-227, 2005. (0.776, 112/153, 2014)
        • 19. WT Wu, CN Chen, CI Lin, JH Chen and H Lee*. Lysophospholipids enhance matrix metalloproteinase-2 expression in human endothelial cells. Endocrinology, 146(8): 3387-400, 2005. (4.503, 28/128, 2014)
        • 20. 李心予*，郭明良，謝豐舟 血管內皮細胞相關研究之回顧與進展Medicine Today, 32(10):825-832, 2005. (in Chinese)
        • 21. WM Hsu, YM Jen, H Lee, ML Kuo, PN Tsao, CN Chen, DM Lai, MT Lin, HS Lai, WJ Chen, FJ Hsieh. The influence of biological factors on the surgical decision in advance neuroblastoma. Ann Surg Oncol. 13(2): 238-244, 2006. (3.930, 15/198, 2014)
        • 22. C.-Y. Pan, H Lee, &C.-L. Chen. Effects of lysophospholipids in modulating the [Ca2+]i and exocytosis in bovine chromaffin cells. Neuropharmacology. 51(1): 18-26, Epublished ahead of print, April 6, 2006. (5.106, 20/254, 2014)
        • 23. CI Lin, CN Chen, JH Chen and H Lee*. Lysophospholipids increase IL-8 and MCP-1 expressions in human umbilical cord vein endothelial cells through an IL-1- and Edg1-dependent mechanism. J Cellular Biochemistry. 99(4): 1216-32, 2006. Epublished ahead of print, June 22, 2006. (3.263, 107/289, 2014)
        • 24. YW Lee, JJ Liao, YT Huang, YT Kuo and H Lee*.The Expression Profiles of LPLs Receptors in Different Endothelial Cells. Taiwania, 51(1): 11-24, 2006.
        • 25. MC Ho, JJ Lin, CN Chen, CC Chen, H Lee, CY Yang, YH Ni, KJ Chang, HC Hsu, FJ Hsieh and PH Lee. A gene expression profile for vascular invasion can predict the recurrence after resection of hepatocellular carcinoma: a microarray approach. Ann Surg Oncl. 13(11): 1474-84, 2006. Epublished ahead of print, Sep 29, 2006. (3.930, 15/198, 2014)
        • 26. SC Hsu, KF Hau, H Lee, LK Chao, SK Tan, H Lee, SF Yang, HY Hsu. LTA and LPS mediated activation of protein kinases in the regulation of inflammatory cytokines expression in macrophage. Clinica Chemica Acta, 374(1-2): 106-15, 2006. Epublished ahead of print, June 10, 2006. (2.824, 5/30, 2014)
        • 27. MC Ho, CN Chen, H Lee, FJ Hsieh, CT Shun, CL Chang, YT Lai, PH Lee. PLGF not VEGF A or C can predict the early recurrence after radical resection of hepatocellular carcinoma. Cancer Letters, 250(2): 237-49, 2006 Nov 28; [Epub ahead of print]. (5.621, 23/211, 2014)
        • 28. YF Liao, BJ Wang, WM Hsu, H Lee, CY Liao, SY Wu, HT Cheng and MK Hu. Unnatural amino acid-substituted (hydroxyethyl) urea peptidomimetics inhibit {gamma}-secretase and promote the neuronal differentiation of neuroblastoma cells. MolPharmacol. 71(2): 588-601, 2007. [Epub ahead of print, 2006 Nov 14] (4.128, 38/254, 2014)
        • 29. CL Chang, JJ Liao, WP Huang*, H Lee*. Lysophosphatidic acid inhibits serum deprivation-induced autophagy in human prostate cancer PC-3 cells. Autophagy. 3(3): 268-270, May 2007. [Epub ahead of print, 2007] (11.753, 15/184, 2014)
        • 30. CI Lin, CN Chen, BW Lin and H Lee*. Sphingosine 1-phosphate regulates inflammation-related genes in human endothelial cells through S1P1 and S1P3. BBRC. 355(4): 894-901, 2007. [Epub ahead of print, 2007Feb 22] (2.297, 41/73, 2014)
        • 31. CI Lin, CN Chen, BW Lin, KJ Chang, FJ Hsieh and H Lee*. Lysophosphatidic acid regulates inflammation-related genes in human endothelial cells throughLPA1 and LPA3. BBRC. 363(4): 1001-1008,2007. [Epub ahead of print, 2007Oct 01] (2.297, 41/73, 2014)
        • 32. YT Huang, YW Lee, JJ Liao, CI Lin, JH Haga, J Li and H Lee*. Sphingosine 1-Phosphate Induces Platelet/Endothelial Cell Adhesion Molecule-1 Tyrosine Phosphorylation in Bovine Aortic Endothelial Cells through a PP2-Inhibitable Mechanism. Taiwania. 52(4): 324-331. 2007.
        • 33. CI Lin, CH Hsieh, JT Wu, WS Lee, GP Chang-Chien, CY Pan and H Lee*. Establish of a FRET detection system for dioxin-like compounds. Chinese Bioscience, 50(1):12-25. 2007.
        • 34. I C Chou, WJ Lee, LC Wang, GP Chang-Chien, WS Lee and H Lee. Validation of the XDS-CALUX bioassay as a screening and semi-quantitation approach in cow’s milk. Journal of Hazardous Materials, 154(1-3):1166-72, Jun 15, 2008. [Epub ahead of print 2007 Nov 17] (4.529, 2/124, 2014)
        • 35. CL Chang, ME Lin, HY Hsu, CL Yao, SM Huang, CY Pan, CY Hsu and H Lee*. Lysophosphatidic acid-induced interleukin-1β expression is mediated through Gi/Rho and the generation of reactive oxygen species in macrophages. J of Biomed. Sci. 15(3): 357-63, 2008. [Epub ahead of print 2007 Nov 25] (2.763, 50/123, 2014)
        • 36. HL Wu*, CI Lin, YL Huang, PS Chen, CH Kuo, MS Chen, GC Wu, GY Shi, HY Yang* and H Lee*. Lysophosphatidic acid stimulates thrombomodulin lectin-like domain shedding in human endothelial cells. BBRC. 367(1): 162-168, 2008. [Epub ahead of print 2007 Dec 29] (2.297, 41/73, 2014)
        • 37. SU Chen, CH Chou, H Lee, CH Ho, CW Lin and YS Yang. Lysophosphatidic acid up-regulates expression of interleukin-8 and -6 in granulosa-lutein cells through its receptors and NF-кB dependent pathways: implications for angiogenesis of corpus luteum and ovarian hyper stimulation syndrome. Journal of Clinical Endocrinology and Metabolism. 93(3): 935-43, 2008. [Epub ahead of print 2008 Jan 2] (6.209, 15/128, 2014)
        • 38. YT Huang, SU Chen, CH Chou and H Lee*. Sphingosine 1-phosphate induces platelet/endothelial cell adhesion molecule-1 phosphorylation in human endothelial cells through cSrc and Fyn. Cell Signaling. 20(8):151-7,2008. [Epublished ahead of print, April18] (4.315, 65/184, 2014)
        • 39. CL Chang, HY Hsu, HY Lin, WC Chiang and H Lee*. Lysophosphatidic acid induced oxidized LDL uptake is class A scavenger receptor dependent in mouse macrophages. Prostaglandins and other lipid mediators. 87(1-4): 20-5. 2008. [Epublished ahead of print, June 8]. (2.377, 171/289, 2014)
        • 40. CI Lin, CH Hsieh, SSY Lee, WS Lee, GP Chang-Chien, CY Pan and H Lee*. Establish of a FRET based bioassay for dioxin-like compounds. J of Biomed. Sci. 15(6): 833-840. 2008. [Epublished ahead of print, July 5]. (2.763, 50/123, 2014)
        • 41. SJ Lee*, TH Chan, TC Chen, CC Huang, BK Liao, PP Huang and H Lee*. LPA1 is essential for proper blood and lymphatic vessel development in zebrafish. FASEB J. 22(10): 3706-15, 2008. [Epublished ahead of print, July 7]. (5.043, 9/85, 2014)
        • 42. SU Chen, H Lee, CH Chou, DY Chang, CY Chang and YS Yang. Lysophosphatidic acid mediates interleukin-8 expression in human endometrial stromal cells through its receptor and nuclear factor-к B dependent pathway: a possible role in angiogenesis of endometrium and placenta. Endocrinology. 149(11): 5888-96. 2008.[Epublished ahead of print, July 10]. (4.503, 28/128, 2014)
        • 43. CI Lin, CN Chen, MT Huang, SJ Lee, CH Lin, CC Chang and H Lee*. Lysophosphatidic acid upregulates vascular endothelial growth factor-C and tube formation in human endothelial cells through LPA1/3, COX-2, NF-kB activation- and EGFR transactivation-dependent mechanisms. Cell Signaling. 20(10): 1804-14. 2008. [Epublished ahead of print, July 21]. (4.315, 65/184, 2014)
        • 44. CI Lin, CN Chen, MT Huang, SJ Lee, CH Lin, CC Chang and H Lee*. Lysophosphatidic acid up-regulates vascular endothelial growth factor-C and lymphatic marker expressions in human endothelial cells. Cellular and Molecular Life Science. 65(17): 2740-51. 2008. [Epublished ahead of print, July 21]. (5.808, 37/289, 2014)
        • 45. LC Hsiung, CH Yang, CL Chiu, CL Chen, Y Wang, H Lee, JY Chen and AM Wo. A planar interdigitated ring electrode array via dielectrophoresis for uniform patterning of cells. Biosensors and Bioelectronics. 24(4): 869-75, 2008. [Epublished ahead of print, July 25]. (6.409, 1/28, 2014)
        • 46. WM Hsu, H Lee, HF Juan, YY Shih, BJ Wang, CY Pan, YM Jeng, HH Chang, MY Lu, KH Lin, HS Lai, WJ Chen, YG Tsai, YF Liao and FJ Hsieh. Identification of GRP75 as an Independent Favorable Prognostic Marker of Neuroblastoma by a Proteomics Analysis. Clin Cancer Res. 14(19): 6237-45, 2008. (8.722, 12/211, 2014)
        • 47. YL Huang, GY Shi, MJ Jiang, H Lee, YW Chou, HL Wu and HY Yang. Epidermal growth factor up-regulates the expression of nestin through the Ras-Raf-ERK signaling axis in rat vascular smooth muscle cells. BBRC.  377(2): 361-6, 2008. [Epublished ahead of print, Oct 10]. 2008 (2.297, 41/73, 2014)
        • 48. CN Chen, JJ Lin, H Lee, YM Cheng, KJ Chang, FJ Hsieh, HS Lai, CC Chang and PH Lee.  Association between Color Doppler Vascularity Index, Angiogenesis-Related Molecules, and Clinical Outcomes in Gastric Cancer. Journal of Surgical Oncology. 99(7): 402-408. 2009. (3.244, 29/198, 2014)
        • 49. CN Chen, CC Chang, TE Su, WM Hsu, YM Cheng, MC Ho, FJ Hsieh, PH Lee, H Lee* and KJ Chang*. Identification of calreticulin as a prognosis marker and angiogenesis regulator in human gastric cancer. Ann Surg Oncol. 16(2): 524-33, 2009. [Epublished ahead of print, Dec 3. 2008] (3.930, 15/198, 2014)
        • 50. IC Chou, YL Wu, LC Wang, GP Chang-Chien and H Lee. Metal interference on luciferase activity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in bioassays of recombinant mouse hepatoma cells. Journal of Hazardous Materials, 165(1-3): 881-5, 2009. [Epublished ahead of print, Nov 5]. (4.529, 2/124, 2014)
        • 51. YL Huang, GY Shi, H Lee, MJ Jiang, BM Huang, HL Wu and HY Yang. Thrombin induces nestin expression via the transactivation of EGFR signalings in rat vascular smooth muscle cells. Cell Signaling. 21(6): 954-68, 2009. [Epublished ahead of print, Feb 23. 2009] (4.315, 65/184, 2014)
        • 52. YL Huang, CM Wu, GY Shi, GC Wu, H Lee, MJ Jiang, HL Wu and HY Yang. Nestin serves as a prosurvival determinant that is linked to the cytoprotective effect of epidermal growth factor in rat vascular smooth muscle cells. Journal of Biochemistry. 146(3): 307-15, 2009. [Epublished ahead of print, May 18. 2009] (2.582, 154/289, 2014)
        • 53. CL Chang, MC Ho, PH Lee, CY Hsu, WP Huang* and H Lee*. S1P5 is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells. American J. of Physiology. 297(2): C451-8, 2009. [Epublished ahead of print, May 27. 2009]. (3.785, 18/83, 2014)
        • 54. YL Huang, SS Lin, SU Chen* and H Lee*.  Tyrosine sulfation of sphingosine 1-phosphate 1 (S1P1) is required for S1P-mediated cell migration in primary cultures of human umbilical vein endothelial cells. Journal of Biochemistry. 146(6): 815-20, 2009. [Epublished ahead of print, Aug 20. 2009]. (2.582, 154/289, 2014)
        • 55. BW Lin, YL Huang, SU Chen* and H Lee*. Lysophosphatidic acid up-regulates MT1-MMP expression through a Gi–dependent pathway in human umbilical vein endothelial cells. Taiwania, 54(4): 375-80, 2009.
        • 56. SU Chen, CH Chou, KH Chao, H Lee, CW Lin, HF Lu and YS Yang. Lysophosphatidic acid up-regulate expression of growth related oncogene alpha, IL-8 and MCP-1 in human first trimester trophoblasts: possible role in angiogenesis and immune regulation. Endocrinology. 151(1): 369-79, 2010. [Epublished ahead of print, Nov 11. 2009] (4.503, 28/128, 2014)
        • 57. SU Chen, CH Chou, CW Lin, H Lee, JC Wu, HF Lu, CD Chen and YS Yang. Signal mechanisms of vascular endothelial growth factor and interleukin-8 in ovarian hyperstimulation syndrome: dopamine targets their common pathways. Human Reproduction. 25(3): 757-67, 2010. [Epublished ahead of print, Dec. 2009] (4.569, 5/79, 2014)
        • 58. YT Tung, WM Hsu, H Lee, WP Huang and YF Liao. The evolutionarily conserved interaction between LC3 and p62 selectively mediates autophagy-dependent degradation of mutant huntingtin. Cell MolNeurobiol. 30(5): 798-806, 2010. [Epub ahead of print Mar 5, 2010] (2.506, 152/252, 2014)
        • 59. CH Lin, JH Lu, and H Lee*. Interleukin-1β Expression Is Required for Lysophosphatidic Acid-Induced Lymphangiogenesis in Human Umbilical Vein Endothelial Cells. International Journal of Inflammation, vol. 2011, Article ID 351010, 7 pages, 2011. doi:10.4061/2011/351010
        • 60. HH Chang, H Lee, MK Hu, PN Tsao, HF Juan, MC Huang, YY Shih, BJ Wang, YM Jeng, CL Chang, SF Huang, YG Tsay, FJ Hsieh, KH Lin, WM Hsu, YF Liao. Notch1 Expression Predicts an Unfavorable Prognosis and Serves as a Therapeutic Target of Patients with Neuroblastoma. Clin Cancer Res.16(17): 4410-20, 2010. (16/166, 6.747, 2009) [Epub ahead of print Aug 24, 2010] (8.722, 12/211, 2014)
        • 61. KC Chen, TP Lee, CL Chiang, CL Chen, YH Yang, BL Chiang, H Lee and AM Wo*. Detection of Circulating Endothelial Cells Via a Microfluidic Disk. Clin Chem. 57(4): 586-92, 2011. [Epublished ahead of print, Feb. 4.  2011] (7.911, 1/30, 2014)
        • 62. YL Huang, WP Huang and H Lee*. Roles of sphingosine 1-phosphate on autophagy. World Journal of Biological Chemistry. 2(2): 25-34, 2011
        • 63. WC Weng, WT Lee, WM Hsu, BE Chang and H Lee*. The role of GRP78/BiP in embryonic development and neurological disorders. JFMA. 110(7): 428-37. 2011. (1.968, 54/153, 2014)
        • 64. LC Hsiung, CL Chiang, CH Wang, YH Huang, CT Kuo, JY Cheng, CH Lin, V Wu, HY Chou, DS Jong, H Lee* and AM Wo*. Dielectrophoresis-based cellular microarray chip for anticancer drug screening in perfusion microenvironments. Lab on Chip. 11(14): 2333-42. 2011. [Epublished ahead of print, June 1.  2011]. (6.115, 6/79, 2014)
        • 65. YC Lu, CN Chen, WM Hsu, ST Chen, CC Chang* and H Lee*. Knockdown of Calreticulin Suppressed Bladder Tumor Growth and Metastasis. Am. J. Patho. 179(3): 1425-1433. 2011. [Epublished ahead of print, June 29, 2011]. (4.591, 9/75, 2014)
        • 66. WM Hsu, ML Che, YF Liao, HH Chang, CH Chen, YM Huang, YM Jeng, J Huang, MJ Quon, H Lee, HC Huang and MC Huang.B4GALNT3 expression predicts a favorable prognosis and suppresses cell migration and invasion via beta 1 integrin signaling in neuroblastoma. Am. J. Patho. 179(3): 1394-1404. 2011. [Epublished ahead of print, July 7, 2011]. (4.591, 9/75, 2014)
        • 67. CL Chiang, ASS Chen, SJ Lee, KC Tsao, PL Chu, CL Yao* and H Lee*. LPA Induces the Erythropoiesis Process through Activating LPA Receptor 3. Stem Cells. 29(11): 1163-73. doi: 10.1002/stem.733. [Epublished ahead of print, Sept. 14. 2011]. 2011. (6.523, 4/68, 2014)
        • 68. ST Chen, YM Jeng, CC Chang, HH Chang, MC Huang, HF Juan, CH Hsu, H Lee, YF Liao, YL Lee, WM Hsu and HS Lai. Insulin-like growth factor II mRNA-binding protein 3 expression predicts unfavorable prognosis in patients with Neuroblastoma. Cancer Sci. 102(12): 2191-8. doi: 10.1111/j.1349-7006.2011.02100.x. [Epublished ahead of print, Oct. 17, 2011]. 2011. (3.523, 72/211, 2014)
        • 69. J Lu, T Tsai, S Choo, S Yeh, R Tang, A Yang, H Lee and J Lu. Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in zebrafish embryos. J Biomed Sci. 18(1): 73 [Epublished ahead of print, Oct. 8, 2011]. 2011. (2.763, 50/123, 2014)
        • 70. YY Shin, H Lee, A Nakagawara, HF Juan, YM Jeng, YG Tsay, DT Lin, FJ Hsieh, CY Pan, WM Hsu and YF Liao. Nuclear GRP75 binds retinoic acid receptors to promote neuronal differentiation of neuroblastoma. Plos One. 6(10): e26236, 2011. (3.234, 8/56, 2014)
        • 71. TC Huang, HY Chang, CY Chen, PY Wu, H Lee, YF Liao, WM Hsu, HC Huang and HF Juan. Silencing of miR -124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR. FEBS Lett. 585(22): 3586-92. [Epublished ahead of print, Oct. 20, 2011]. 2011. (3.169, 25/73, 2014)
        • 72. YY Shi, A Nakagawara, H Lee, HF Juan, YM Jeng, DT Lin, YL Yang, YG Tsay, MC Huang, WM Hsu and YF Liao. Calreticulin mediates nerve growth factor-induced neuronal differentiation. J of Mol Neurosci. 47(3): 571-81. [Epublished ahead of print, Dec 7, 2011] 2012. (2.343, 174/289, 2014)
        • 73. YT Tung, BJ Wang, MK Hu, WM Hsu, H Lee, WP Huang and YF Liao. Autophagy: A double-edged sword for Alzheimer’s disease. J. Biosci. 37(1): 157-65. 2012. (2.064, 24/85, 2014)
        • 74. TC Tsai, JK Lu, SL Choo, SL Yeh, RB Tang, H Lee and JH Lu. The paracrine effects of exogenous growth hormone alleviate dysmorphogenesis caused by tbx5 deficiency in zebrafish (Danio rerio) embryos. J Biomed. Sci. 19(1): 63. [Epublished ahead of print, July 9, 2012] 2012. (2.763, 50/123, 2014)
        • 75. CE Lin, SU Chen, CC Lin, CH Chang, YL Tai, TL Shen and H Lee*. Lysophosphatidic acid acts as an autocrine factor to enhance vascular endothelial growth factor-C expression in human prostate cancer PC-3 Cells. Plos One. 7(7): e41096. June 2012. (3.234, 8/56, 2014)
        • 76. JT Lin, YS Chiang, GH Lin, H Lee and HW Liu. In vitro photothermal destruction of cancer cells using gold nanorods and Pulsed-train Near-infrared Laser. J. Nanomaterials.e861385. June 2012. (1.644, 121/259, 2014)
        • 77. CT Kuo, CL Chiang, Ruby Huang, H Lee* and AW Wo*. Configurable 2D and 3D tissue cultures on bioengineered surfaces with acquisition of epithelial-mesenchymal transition characteristics. NPG Asia Materials. 4: e27. DOI: 10.1038/am.2012.50. Sep. 2012. (10.118, 14/259, 2014)
        • 78. MY Lu, YL Liou, HH Chang, ST Jou, YL Yang, KH Lin, DT Lin, YL Lee, H Lee, PY Wu, TY Luo, LH Shen, SF Huang, YF Liao, WM Hsu and KY Tzen. Characterization of neuroblastic tumors using 18F-FDOPA PET. J. Nuc. Med.54(1): 42-9. [Epublished ahead of print, Dec 4, 2012] 2013. (6.160, 4/125, 2014)
        • 79. BJ Wang, YF Liao, YT Tung, LH Yih, CC Hu* and H Lee*. Establishment of a Bioluminescence Resonance Energy Transfer (BRET)-based bioassay for detecting dioxin-like compounds. Toxicology Mechanisms and Methods. 23(4): 247-54.[Epublished ahead of print, Nov. 29, 2012] 2013. (1.517, 67/87, 2014)
        • 80. CH Chang, YL Huang, MK Shyu, SU Chen, CS Lin, TK Ju, JH Lu and H Lee*.  Sphingosine 1-phosphate induced vascular endothelial growth factor-C is MMP-2/FGF-1/FGFR-1-dependent in endothelial cells. ActaPharmacologicaSinica.34(3): 360-6. [Epublished ahead of print, Feb. 4, 2013] 2013 (2.912, 44/157, 2014)
        • 81. HH Chang, CH Chen, YF Liao, MJ Huang, YH Chen, WJ Wang, J Huang, JS Hung, WL Ho, YM Jeng, MI Che, H Lee, MY Lu, YL Yang, ST Jou, DT Lin, KH Lin, WM Hsu and MC Huang.β-1, 4-galactosyltransferase III enhances invasive phenotypes via β1 integrin and predicts poor prognosis in neuroblastoma. Clinical Cancer Research. 19(7): 1705-16. [Epublished ahead of print, Feb. 26, 2013] 2013. (8.722, 12/211, 2014)
        • 82. BJ Wang, PY Wu, YC Lu, CH Chang, YC Lin, TC Tsai, MC Hsu and H Lee*. Establishment of a cell-free bioassay for detecting dioxin like compounds. Toxicology Mechanisms and Methods. (6): 464-470. [Epublished ahead of print, Mar. 11, 2013] 2013. (1.517, 67/87, 2014)
        • 83. WM Hsu, CC Huang, PY Wu, H Lee, MC Huang, MH Tai and JH Chuang. Toll-like receptor 3 expression inhibits cell invasion and migration and predicts a favorable prognosis in neuroblastoma. Cancer Letters. 336(2): 338-46. Doi: pil: S0304-3835 (13): 00252-8. 10.1016/j.canlet.2013.03.024. 2013. (5.621, 23/211, 2014)
        • 84. H Lee, KW Chang, HY Yang, BW Lin, SU Chen and YL Huang. MT1-MMP regulates MMP-2 expression and angiogenesis-related functions in human umbilical vein endothelial cells. BBRC. 437(2): 232-8. [Epublished ahead of print, June. 22, 2013] 2013. (2.297, 41/73, 2014)
        • 85. PY Wu, YC Lin, SY Lan, YL Huang and H Lee*. Aromatic hydrocarbon receptor inhibits lysophosphatidic acid-induced vascular endothelial growth factor-A expression in PC-3 prostate cancer cells. BBRC. 437(3): 440-445. [Epublished ahead of print, July 3, 2013] 2013. (2.297, 41/73, 2014)
        • 86. ZR Wong, PH Su, KW Chang, BM Huang, H Lee and HY Yang. Identification of a rod domain-truncated isoform of nestin, Nes-Sd107-254, in rad dorsal root ganglia.  Neurosci Lett. 553:181-185. doi:pii: S0304-3940(13)00768-4. 10.1016/j.neulet.2013.08.035. [Epub ahead of print, Aug. 29, 2013] 2013. (2.030, 173/252, 2014)
        • 87. CC Lin, CE Lin, YC Lin, TK Ju, YL Huang, MS Lee, JH Chen and H Lee*. Lysophosphatidic acid induces reactive oxygen species generation by activating protein kinase C in PC-3 human prostate cancer cells. BBRC. 440(4): 564-569. [Epub ahead of print, Oct 7, 2013] 2013. (2.297, 41/73, 2014)
        • 88. YL Huang, CL Chang, CH Tang, YC Lin, TK Ju, WP Huang* and H Lee*. Extrinsic sphingosine 1-phosphate activates S1P5 and induces autophagy through generating endoplasmic reticulum stress in human prostate cancer PC-3 cells. Cell Signaling. 26(3): 611-618. [Epub ahead of print, Dec 10, 2013] 2014. (4.315, 65/184, 2014)
        • 89. CT Kuo, CL Chiang, CH Chang, HK Liu, GS Huang, RY Huang, H Lee*, CS Huang* and AM Wo*.  Modeling of cancer metastasis and drug resistance via biomimetic nano-cilia and microfluidics. Biomaterials. 35(5): 1562-1571, 2014. (8.557, 2/76, 2014)
        • 90. PY Wu, YF Liao, HF Juan, BJ Wang, YY Shih, YM Jeng, WM Hsu* and H Lee*.  Aryl hydrocarbon receptor down regulates MYCN expression and promotes cell differentiation of Neuroblastoma. Plos One. 9(2): e88795. Feb. 21, 2014. (3.234, 8/56, 2014)
        • 91. YC Lu, CN Chen, CY Chu, JH Lu, BJ Wang, CH Chen, M Chuang, TH Lin, CC Pan, SS Chen, WM Hsu, YF Liao, PY Wu, HY Hsia, CC Chang* and H Lee*.  Calreticulin activates beta1 integrin through fucosylation modification by fucosyltransferase-1 in J82 human bladder cancer cells. Biochemical Journal. 460(1): 69-78. [Epub ahead of print, Mar 1, 2014] 2014. (4.396, 67/289, 2014) (Schwartz M: F1000Prime Recommendation of [Lu YC et al., Biochem J 2014, 460(1): 69-78]. In F1000Prime, 17 Jun 2014; F1000Prime.com/718300946#eval793496276)
        • 92. CT Kuo, HK Liu, GS Huang, CH Chang, CL Chen, KC Chen, RYJ Huang, CH Lin, H Lee*, CS Huang* and AM Wo*. A spatiotemporally defined in-vitro microenvironment for controllable signal delivery and drug screening. Analyst. 139(19): 4846-54, 2014. (4.107, 7/74, 2014)
        • 93. CT Kuo, FT Chuang, PY Wu, YC Lin, HK Liu, GS Huang, TC Tsai, CY Chi, AM Wo, H Lee* and SC Lee*. Experimental demonstration of bindingless signal delivery in human cells via microfluidics. Journal of Applied Physics.  116: 044702, 2014. (2.183, 41/143, 2014)
        • 94. CN Chen, CC Chang, HS Lai, YM Jeng, CI Chen, KJ Chang, PH Lee and H Lee*. Connective tissue growth factor inhibits peritoneal metastasis through blocking integrin a3b1-dependent adhesion in gastric cancer. Gastric Cancer. 18(3): 504-15. [Epub ahead of print, July 2, 2014] 2015. (3.719, 23/76, 2014)
        • 95. WC Weng, KH Lin, PY Wu, YF Liao, WM Hsu, WT Lee and H Lee*. Calreticulin regulates VEGF-A in neuroblastoma cells.  Molecular Neurobiology.  52(1): 758-70. [Epub ahead of print, Oct 7, 2014] 2015. (5.137, 36/252, 2014)
        • 96. YH Ho, CL Yao, KH Lin, FH Hou, WM Chen, CL Chiang, YN Lin, MW Li, SH Lin, YJ Yang, CC Lin, J Lu*, G Tigyi* and H Lee*. Opposing regulation of megakaryopoiesis by LPA receptor 2 and 3 in K562 human erythroleukemia cells. BBA Molecular and Cell Biology of Lipid. 1851(2): 172-83, [Epub ahead of print, Nov 21, 2014] 2015. (5.162, 47/289, 2014)
        • 97. YC Lu, WC Weng and H Lee*. Functional roles of calreticulin in cancer biology. Biomedical Research International. Volume 2015, Article ID 526524, 2015.  (1.579, 107/163, 2014)
        • 98. WM Hsu, CC Huang, H Lee, PY Wu, MT Wu, HC Chuang, LL Lin and JH Chuang. MDA5 complements TLR3 in suppression of neuroblastoma. Oncotarget. 6(28): 24935-46, [Epub ahead of print, July 9, 2015] 2015.
        • 99. H Lee* and MH Gräler. Lysophospholipid signaling in cancer and immunity at a glance. Translational Cancer Research. 4(5): 451-452. 2015.
        • 100. RJ Chen, CH Chou, SU Chen and H Lee. Angiogenic effect of lysophosphatidic acid receptors on cervical cancer cells. Translational Cancer Research. 4(5): 500-526. 2015.
        • 101. YC Lin, YL Huang and H Lee*. Lysophosphatidic acid in prostate cancer progression. Translational Cancer Research. 4(5): 527-536. 2015.
        • 102. CK Han, HC Chiang, CY Lin, CH Tang, H Lee, DD Huang, YR Zeng, TN Chuang and YL Huang.  Comparison of immunomodulatory and anticancer activities in different strains of Tremella fuciformis berk.  Am J Chin Med. 43(8): 1637-55. 2015.
        • 103. DJ Klionsky et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12(1): 1-222. 2016. (11.753, 15/184, 2014)
        • 104. CY Kuo, CY Chi, PY Wu, FT Chuang, YC Lin, HK Liu, GS Huang, TC Tsai, AM Wo, H Lee and SC Lee. Observation of “wired” cell communication over 10-um and 20-um poly (dimethylsilosane) barriers in tetracycline inducible expression systems. Journal of Applied Physics.  119(2): 024702, 2016. (2.183, 41/143, 2014)
          105. YL Liu, MY Lu, HH Chang, CC Lu, DT Lin, ST Jou, YL Yang, YL Lee, SF Huang, YM Jeng, H Lee, JS Miser, KH Lin, YF Liao, WM Hsu and KY Tzen. Diagnostic FDG and FDOPA positron emission tomography scans distinguish the genomic type and treatment outcome of neuroblastoma.  Oncotarget. [Epub ahead of print, March 5, 2016] 2016.
          106. KH Lin, YS Ho, JC Chiang, MW Li, SH Lin, WM Chen, CL Chiang, YN Lin, YJ Yang, CN Chen, J Lu, CJ Huang, G Tigyi. CL Yao* and H Lee*. Pharmacological activation of LPA receptors regulates erythropoiesis. Scientific Reports. 6:27050. May 31st 2016.
          107.K Hsia, CL Yao, WM Chen, JH Chen, H Lee* and J Lu*. Scaffolds and cell-based tissue engineering for blood vessel therapy. Cells Tissues Organs. DOI: 10.1159/000448169. Aug 23rd 2016.
          108.Tai YL, Tung LH, Lin YC, Lu PJ, Chu PY, Wang MY, Huang WP, Chen KC, Lee H and Sen TL. Grb7 protein stability modulated by Pin 1 in association with cycle progression. PLoS One. 11(9): e0163617. Sep 22, 2016.
          109. Abiko Y, Lin FY, Lee H, Puga A and Kumagai Y. Quinone-mediated induction of cytochrome P450 1A1 in HepG2 cells through increased interaction of aryl hydrocarbon receptor with aryl hydrocarbon receptor nuclear translocator. J Toxicol Sci. 41(6): 775-781. 2016.
          110. Chang HH, Liu YL, Lu MY, Jou ST, Yang YL, Lin DT, Lin KH, Tzen KY, Yen RF, Lu CC, Liu CJ, Peng SS, Jeng YM, Huang SF, Lee H, Juan HF, Huang MC, Liao YF, Lee YL, Hsu WM. A multidisciplinary team care approach improves outcomes in high-risk pediatric neuroblastoma patients. Oncotarget. doi: 10.18632/oncotarget.13874. Dec 10, 2016. [Epub ahead of print]
          111. Hsia K, Yang MJ, Chen WM, Yao CL, Lin CH, Loong CC, Huang YL, Lin YT, Lander AD, H Lee* and J Lu*. S1P improves endothelialization with reduction of thrombosis in re-cellularized human umbilical vein graft by inhibiting syndecan-1 shedding in vitro.  Acta Biomaterialia. Accepted, 2017.
        • 112. Wang BJ, Her GM, Hu MK, Chen YW, Tung YT, Wu PY, Lee H, Jin LW, Huang, SL, Chen RP, Huang CJ and Liao YF. ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America, 114(15): E3219-E3138. [Epub ahead of print, Mar 28, 2017], 2017. (9.674, 4/56, 2014)
          113. Kuo CT, Wang JY, Wo AM, Chen BP* and H Lee*. ParaStamp and its application to cell patterning, drug synergy screening, and rewritable devices for droplet storage. Advanced Biosystems. DOI: 10. 1002/abdi.201770024. [Epub ahead of print, Apr. 25, 17], 2017. (Selected as cover image)
          114. Kuo CT, Wang JY, Lin YF, Wo AW, Chen BP* and H Lee*. Three-dimensional spheroid culture targeting versatile tissue bioassays using a PDMS-based hanging drop array. Scientific Reports. 7(1): 4363. Jun 29, 2017.
          115. Weng WC, Lin KH, Wu PY, Ho YS, Liu YL, Wang BJ, Chen CC, Liao YF, Lee WT, Hsu WM* and H Lee*. VEGF expression correlates with neuronal differentiation and predicts a favorable prognosis in patients with neuroblastoma. Scientific Reports. 7(1): 11212. Sep 11, 2017.
          116.Lin YC, Ohbayashi N, Hongu T, Katagiri N, Funakoshi Y, Lee H and Kanaho Y. Arf6 in lymphatic endothelial cells regulates lymphangiogenesis by controlling directional cell migration. Scientific Reports. 7(1): 11240. Sep 12, 2017.
        • 117. Lin KH, Li MW, Chang YC, Lin YN, Chang BE, Huang CJ, Yao CL* and Lee H*. Activation of lysophosphatidic acid receptor 3 inhibits megakaryopoiesis in human hematopoietic stem cells and zebrafish.  Stem Cells and Development. 27 (3): 216-224. doi: 10.1089/scd.2017.0190. [Epub ahead of print Dec 14, 2017], 2018. (3.562, 34/128, 2016)
        • 118. Lin YF, Shih HY, Shang ZF, Guo J, Du C, Lee H and BPC Chen. PIDD mediates the association of DNA-PKcs and ATR at stalled replication forks to facilitate the ATR signaling pathway. Nucleic Acid Research. 46(4): 1847-1859. doi: 10.1093/nar/gkx1298. [Epub ahead of print Jan 4, 2018], 2018 (10.162, 14/290, 2016)
        • 119. Lee CY, Hsieh PH, Chiang LM, Chattopadhyay A, Li KY, Lee YF, Lu TP, Lai LC, Lin EC, Lee H, Ding ST, Tsai MH, Chen CY and Chuang EY.  Whole-genome de novo sequencing reveals unique genes that contributed to the adaptive evolution of the Mikado pheasant. Gigascience. doi: 10.1093/gigascience/giy044. [Epub ahead of print May 4th, 2018], 2018.  (6.681, 6/64, 2016)
        • 120. Kuo CT, Lu SR, Chen WM, Wang JY, Lee SC, Chang HH, Wo AM, Chen BPC, Lee H*. Facilitating tumor spheroid-based bioassays and in vitro blood vessel modeling via bioinspired self-formation microstructure devices. Lab on a Chip. 18: 2453-2465. doi: 10.1039/c8lc00423d. [Epub ahead of print July 18, 2018], 2018.
        • 121. Lin CH, Hsia K, Ma H, Lee H, Lu JH. In vivo performance of de-cellularized vascular grafts: A review article. Int J Mol Sci. 19(7). pii: E2101. doi: 10.3390/ijms19072101. 2018. Review.
        • 122. Lin YC, Chen CC, Lu KY, Chen WM, Shen TL, Jou YC, Shen CH, Ohbayashi N, Kanaho Y, Huang YL and Lee H*. LPA1/3 signaling mediates tumor lymphangiogenesis through promoting CRT expression in prostate cancer. BBA Molecular and Cell Biology of Lipid. 1863: 1305-1315, 2018.
        • 123. Huang YL, Lin YC, Lin CC, Chen WM, Chen BPC, and Lee H*. High glucose induces VEGF-C expression via the LPA1/3-AKT-LEDGF signaling axis in human prostate cencer PC-3 cells. Cellular Physiology and Biochemistry. Accepted, 2018.
        • 124. Yang JH, Chen CD, Chou CH, Wen WF, Tsao PN, Lee H and Chen SU. Intentional endometrial injury increases embyro implantation potentials through enhanced endometrial angiogenesis. Biology of Reproduction. doi: 10.1093/biolre/ioy205. [Epub ahead of print Sep 21, 2018]. 2018.
        • 125. Wu PY, Lin YC, Huang YL, Chen WM, Chen CC* and Lee H*. Mechanisms of lysophosphatidic acid-mediated lymphangiogenesis in prostate cancer. Cancers. 10(11): 413; doi: 103390/cancers01110413. 2018.
        • 126. Lee AC, Shih YY, Zhou F, Chao TC, Lee H, Liao YF, Hsu WM and Hong JH. Calreticulin regulates MYCN expression to control neuronal differentiation and stemness of neuroblastoma. Journal of Molecular Medicine. Jan 5, 2019. doi: 10.1007/s00109-018-1730-x. [Epub ahead of print]
        • 127. Hsia K, CH Lin, Lee H, Chen WM, CL Yao, Chen CC, MA H, Wang SJ and Lu JH. S1P in endothelial cell recellularization improves patency and endothelialization of decellularized vascular grafts in vivo. Int J Mol Sci. 20(7):1641. doi: 10.3390/ijms20071641. 2019.
        • 128.  Lee CF, A Dang, E Hernandez, RC Pong, B Chen, R Sonavane, G Raj, P Kapur, HY Lin, SR Wu, CJ Ko, UG Lo, H Lee, JT Hsieh and MS Lee. Activation of sphingosine kinase by lipopolysaccharide promotes prostate cancer cell invation and metastasis via SphK1/S1PR4/matripase. Oncogene. Doi:org/10/1038/s41388-019-0833-3. 2019.
        • 129.  Kuo CT, Wang JY, Lu SR, Lai YS, Chang HH, Hsieh JT, Wo AM, Chen BPC, Lu JH, Lee H*. A nanodroplet cell processing platform facilitating drug synergy evaluations for anti-cancer treatments. Scientific Reports. 9(1): 10120. July 12, 2019.
        • 130.  Lu JK, Tsai TC, Lee H, Hsia K, Lin CH, Lu JH. Pectoral fin anomalies in tbx5a knockdown zebrafish embryos related to the cascade effect of n-cadherin and extracellular matrix formation. J Dev Biol. 7(3). pii: E15. doi: 10.3390/jdb7030015. July 12, 2019.
        • 131.  Wu PY, Chuang PY, Chang GD, Chan YY, Tsai TC, Wang BJ, Lin KH, Hsu WM*, Liao YF* and Lee H*. Novel endogenous ligands of aryl hydrocarbon receptor mediate neural development and differentiation of neuroblastoma. ACS Chem Neurosci. 10(9): 4031-4042. Doi: 10.1021/acschemneuro.9b00273. Sep 18th, 2019.
        • 132.  Wu PY, Yu IS, Lin YC, Chang YT, Chen CC, Lin KH, Tseng TH, Kargren M, Tai YL, Shen TL, Liu YL, Wang BJ, Chang CH, Chen WM, Juan HF, Huang SF, Chan YY, Liao YF*, Hsu WM* and Lee H*. Activation of Aryl Hydrocarbon Receptor by Kynurenine Impairs Progression and Metastasis of Neuroblastoma. Cancer Res. 79 (21): 5550-5562. Doi: 10.1158/0008-5472.CAN-18-3272. Nov 1st, 2019.
        • 133.  Lin CH, Lu JH, Hsia K, Lee H, Yao CL and Ma H. The antithrombotic function of S1P on human adipose stem cell recellularized tissue engineered vascular graft in vitro. Int J Mol Sci. 20(20): 5218. doi: 10.3390/ijms20205218. Oct 21st, 2019.
        • 134.  Chen WM, Chiang JC, Lin YC, Lin YN, Chuang PY, Chang YC, Chen CC, Wu KY, Hsieh JC, Chen SK, Huang WP, Chen BPC* and Lee H*. Lysophosphatidic acid receptor LPA3 prevents oxidative stress and cellular senescence in Hutchinson–Gilford progeria syndrome. Aging Cell. 2019;00:e13064.
        • 135.  Lee PC, Chiang JC, Chen CY, Chien YC, Chen WM, Huang CW, Weng WC, Chen CI, Lee PH, Chen CN, Lee H*. Calreticulin regulates vascular endothelial growth factor-A mRNA stability in gastric cancer cells. PLoS One. 14(11): e0225107. doi: 10.1371/journal.pone.0225107. eCollection. Nov 14, 2019.

         

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    Abstracts:

              • 1. RI Weiner, G D’Angelo, H Lee, J Martial, C Clapp. The 16Kda N-terminal fragment of prolactin is an antiangiogenic factor. Abstracts VIth International Congress of Prolactin, Neuroendocrinology 58(S1): 50, 1993
                2. RI Weiner, G D’Angelo, H Lee, J Martial, C Clapp. The 16Kda N-terminal fragment of prolactin (16K PRL) is a potent antiangiogenic factor. Endocrine Society Program, 76th Meeting: 176, 1994
                3. H Lee, C Clapp, RI Weiner. 16 Kda N-terminal fragment of prolactin inhibits the stimulation of urokinase by bFGF. Endocrine Society Program, 77th Meeting: 277, 1995
                4. H Lee, RI Weiner. 16K PRL increases plasminogen activator inhibitor-1 expression in capillary endothelial cells. Endocrine Society Program, 79th Meeting: 437, 1997
                5. H Lee, F Bentzien, JF Martini, R Woodward, I Struman, J Martial, RI Weiner. Signaling pathways for the antiangiogenic actions of 16K PRL and TGF-B. Endocrine Society Program, 80th Meeting: 500, 1998.
                6. H Lee, EJ Goetzl, S An. Effects of lysophosphatidic acid and sphingosine 1-phosphate on endothelial cells. FASEB J, 13(5): A706, 1999.
                7. EJ Goetzl, H Lee, T Azumi, TP Stossel, JS Karliner. Gelsolin (GS) binding of lysophosphatidic acid and enhancement of presentation of LPA to rat cardiac myocytes (RCMs). FASEB J, 13(7): A1423, 1999
                8. H Lee, EJ Goetzl, S An. Lysophosphatidic acid and sphingosine 1-phosphate stimulate endothelial cell wound healing. New York Academic of Science Meeting. June 1999.
                9. H Lee, EJ Goetzl, S An. Lysophospholipids increase PECAM expression on endothelial cells. FASEB J, 14(4): A414, 2000.
                10. H Dolezalova, MD Cunningham, DE Solow-Cordero, Y Kong, H Lee and EJ Goetzl. Cellular presentation of lysophosphatidic acid (LPA) by the human plasma gelsonlin (GE) substituent peptide GE135-169. FASEB J, 14(8):A1464, 2000.
                11. H Lee, EJ Goetzl. Differential effects of lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) on signaling of endothelial cells. FASEBJ, 15(5):A111, 2001.
                12. H Lee, EJ Goetzl. Enhancement of endothelial cell adhesion to type I collagen by lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). FASEBJ, 15:LB31, 2001.
                13. EJ Goetzl, G Dorsam, H Lee, Y Kong, JK Voice. Allergic diathesis in transgenic mice with T cell over-expression of the type II receptor for vasoactive intestinal peptide. Clin. Immunol. 99:117, 2001.
                14. JJ Liao, KX Wu, EJ Goetzl, H Lee. Lysophospholipids increase ICAM-1 expression in human umbilical cord vein endothelial cells (HUVEC) through a Gi-dependent mechanism. FASEB J. 16(4): A440, 2002
                15. ME Lin, CL Zhang, JJ Liao, EJ Goetzl, H Lee. Lysophospholipids increase IL1  and TNF  expression in the J774A.1 mouse macrophage through a Rho-dependent mechanism. FASEB J. 16:LB33, 2002.
                16. YW Lee, JJ Liao, J Haga, J Li, S Chien and H Lee. Sphingosine-1-Phosphate Induces PECAM-1 Tyrosine Phosphorylation in Endothelial Cell. FASEB J. 18(5): A1000. 2004.
                17. H Lee, CI Lin, YW Lee, JJ Liao, WF Yen and JH Chen. Lysophospholipids enhance IL-8 and MCP-1 expression in human endothelial cells. FASEB J.18(4):A637. 2004.
                18. WT Wu and H Lee. Lysophospholipids induce matrix mataloproteinases. Acta Zoologica Taiwanica. 14(2): 107. 2004
                19. C Lin and H Lee. Enhancement effects of lysophospholipids on ICAM-1, IL8 and MCP-1 expression on human endothelial cells. Acta Zoologica Taiwanica. 14(2): 111. 2004
                20. CL Chang and H Lee. The mechanisms of LPA-induced IL-1 beta expression in J774A.1 mouse macrophage cell line. Acta Zoologica Taiwanica. 14(2): 119. 2004
                21. CW Chen,MC Sung, CP Ten and H Lee. Comparison of luciferase base dioxin detection system using fish and mammalian cells. Acta Zoologica Taiwanica. 14(2): 133. 2004
                22. AT Ku, JL Hsu,CY Ding and H Lee. Comparison of dioxin-induced nuclear translocation AHR between mammalian and Fish Cells. Acta Zoologica Taiwanica 14(2): 153. 2004
                23. JJ Liao and H Lee. Anti proliferative properties of sphingosine 1-phosphate in human prostate cancer PC-3 Cell Lines. Acta Zoologica Taiwanica. 14(2): 155. 2004
                24. YC Chen and H Lee. Sphingosine 1-Phosphate Induces PECAM-1 phosphorylation through activating cSrc. Acta Zoologica Taiwanica. 14(2): 159. 2004
                25. CL Chang,ME Lin, HY Lin, W Chiangand H Lee. The molecular mechanisms of lysophophatidic acid-induced IL-1 beta expression and the regulation of inflammation-related functions in mouse macrophages. FASEB J 19:A698. 2005
                26. H Lee, WT Wu, JN Chenand JH Chen. Lysophospholipids enhance matrix metalloproteinase-2 expression in human endothelial cells. FASEB J 19:A1267. 2005
                27. CI Lin, TE Su, CY Kao, CH Linand H Lee.Lysophospholipids enhances IL-8 and MCP-1 expression in human umbilical cord vein endothelial cells through an IL-1- and Edg1-dependent mechanism. FASEB J 19:A1268. 2005.
                28. CI Lin, YT Huang, CY Kao and H Lee.Sphingosine 1-phosphate enhances ICAM-1 expression in human umbilical cord vein endothelial cells through an Edg1-dependent mechanism. FASEB J 19:A1268. 2005.
                29. JJ Liao, YT Kuo, YT Huang and H Lee.Inhibitory effect of sphingosine-1-phosphate on proliferation of PC-3 human prostate cancer cell line. FASEB J 19:A1971. 2005.
                30. CI Lin and H Lee. Study of lysophospholipids on ICAM-1, IL-8 and MCP-1 expression on human endothelial cell through an Edg-1 and IL-1-dependent mechanism. Acta Zoologica Taiwanica. 15(1):25. 2005
                31. CL Changand H Lee. LPA induces IL-1b expression, reaction oxygen species production, and oxidized-LDL uptake in mouse macrophages. Acta Zoologica Taiwanica15(1):59. 2005
                32. H Lee, CI Lin, WT Wu. Sphingosine 1-phosphate enhances tissue inhibitor of metalloproteinases (TIMPs) expression in human endothelial cells. FASEB J. 20(1):C419.2006.
                33. CI Lin, CH Hsieh, GP Cheng-Jeng, JT Wu, H Lee.Establishment of a novel biological detection system for dioxin-like compounds by fluorescence resonance energy transfer (FRET). FASEB J.20(1):C596. 2006.
                34. WP Huang, JJ Liao, H Lee. Lysophosphatidic acid (LPA) Inhibits Serum Starvation Induced-autophagy of PC-3 Human Prostate Cancer Cell-Line. FASEB J. 20(1): C846. 2006.
                35. T Chen, K Tsao, T Chen, H Lee, S Lee. Knock down of Edg2 inhibits heart contraction and blood circulation in Zebrafish. ASCB Meeting. San Diego, Dec. 2006.
                36. MT Huang, YB Chou, H Lee, FJ Shieh, PJ Chen, BL Chiang. Regulatory T Cells Alleviate Allergic Airway Hyper-responsiveness by Modulating Angiogenesis in Airway Remodeling. FASEB J. 21(6): A762. 2007.
                37. MT Huang, CY Liu, H Lee, FJ Shieh, PJ Chen, BL Chiang. Suppressor and Effector T Cells Exhibit Differential Migration Capacity. FASEB J. 21(6): A773. 2007.
                38. HS Lin, HF Juan, H Lee. Study of the Effects of Tyrosine Sulfation of S1P1 on Human Endothelial Cell. FASEB J. 21(6): A857. 2007.
                39. H Lee, CI Lin, PW Lin. Lysophospholipids Enhance Membrane Type-1 Matrix Metalloproteinases Expression Activity in Human Endothelial Cells. FASEB J. 21(5): A858. 2007.
                40. CI Lin, CN Chen, HL Wu, H Lee. Expression and Function of the Lysophospholipids Receptors, S1P1 and LPA1, in Human Endothelial Cells and the Regulation of Inflammation-Related Genes. FASEB J. 21(6): A858. 2007.
                41. CN Chen, TN Su, YC Lu, H Lee. Calreticulin Regulates Cell Proliferation and Migration in Gastric Cancer Cell Line AGS. FASEB J. 21(6): A1318. 2007.
                42. YT Kuo, JJ Liao, CL Chang, H Lee. Lysophosphatidic Acid (LPA) Enhances Matrix Metalloproteinase-2 (MMP-2) Expression in PC-3 Human Prostate Cancer Cell Line. FASEB J. 21(6): A1429. 2007.
                43. CL Chang, YC Perng, CK Yao, SM Hwang, H Lee. Lysophosphatidic Acid Induces IL-1 Expression and Reactive Oxygen Species Production in Human Macrophages. FASEB J. 21(6): LB102. 2007.
                44. CH Hsieh, CI Lin, H Lee. Establish a novel FRET-based bioassay for detection of dioxin-like compounds. FASEB J.22: 921.2. 2008
                45. CI Lin, CN Chen, MT Huang, SJ Lee, H Lee. Lysophosphatidic acid upregulates vascular endothelial growth factor-C expression in human endothelial cells and enhances lymphangiogenesis. FASEB J. 22: 964.19. 2008.
                46. YT Huang, H Lee. Sphingosine 1-phosphate induces platelet/endothelial cell adhesion molecule-1 phosphorylation in human endothelial cells through cSrc and Fyn. FASEB J. 22: 964.36. 2008
                47. CL Chang, CY Hsu, MC Ho, PH Lee, H Lee, WP Huang. Sphingosine 1-phosphate (S1P) induces autophagy of PC-3 human prostate cancer cell-line. FASEB J.22: 1238.21. 2008
                48. CL Chang, HY Hsu, HY Lin, W Chiang, H Lee. Lysophosphatidic acid induced oxidized low-density lipoprotein uptake is mediated through activation of Gi and expression of scavenger receptor class-A in mouse macrophages. FASEB J. 22: 924.10. 2008
                49. CH Lin, CI Lin, H Lee. Interleukin 1β (IL-1β) expression is required for lysophosphatidic acid (LPA)-induced lymphangiogenesis in endothelial cells. FASEB, 23:965.9, 2009
                50. YC Lu, CC Chang, H Lee. Calreticulin-Knockdown Suppresses Cell Proliferation, Migration and Adhesion in Human Bladder Cancer Cells. FASEB, 23:740.17, 2009
                51. PY Wu, WM Hsu, H Lee. Aromatic Hydrocarbon Receptor Down-regulates MYCN Expression and Promotes Neural Differentiation of Neuroblastoma. FASEB, 23:740.15, 2009
                52. PW Lin, H Lee. Knockdown of MT1-MMP expression in Human Umbilical Vein Endothelial Cell Inhibits MMP-2 and TIMP-2 expression. FASEB, 23:965.8, 2009
                53. CL Chang, CN Chen, H Lee, WP Huang. Sphingosine 1-phosphate (S1P)-induced autophagy plays a protective role in human prostate PC-3 cells. FASEB, 23:618.11, 2009
                54. PY Wu, WM Hsu, H Lee. Aromatic Hydrocarbon Receptor Down-regulates MYCN Expression and Promotes Neural Differentiation of Neuroblastoma. AEARU, P168, 2009
                55. CE Lin, CH Lin, CL Chang, WP Huang and H Lee. LPA enhances VEGF-C expression in PC-3 human prostate cancer cells. FASEB 2010: 954.8, P289, 2010.
                56. CJ Shih, YL Huang, CL Chang, WP Huang and H Lee. S1P-induced autophagy is mediated through activating ER stress responses in human prostate cancer PC-3 cells. FASEB 2010: 954.9, P289, 2010.
                57. MSY Kao, CH Chang and H Lee. Characterization of LPA4 and LPA5 in zebrafish. FASEB 2010: 988.9, P306, 2010.
                58. WM Hsu, YY Shih, H Lee, HF Juan, YG Tsay, YF Liao: The interaction between GRP75 and retenoic acid receptor-α/retenoid X receptor-α is essential for retenoic acid-induced neuronal differentiation of neuroblastoma cells. Advances in Neuroblastoma Research June 21-24, 2010, Stockholm, Sweden.
                59. HH Chang, WM Hsu, HF Juan, YF Liao, MC Huang, H Lee, FJ Hsieh, KH Lin: Microarray-based pathway analysis leads to the identification of potential molecular mechanisms underlying gamma-secretase inhibitor-induced differentiation. Advances in Neuroblastoma Research June 21-24, 2010, Stockholm, Sweden.
                60. WM Hsu, PY Wu, HF Juan, H Lee: Aromatic hydrocarbon receptor down-regulates MYCN expression and promotes neuronal differentiation of neuroblastoma. Advances in Neuroblastoma Research June 21-24, 2010, Stockholm, Sweden.
                61. HH Chang, WM Hsu, MC Huang, YF Liao, H Lee, HF Juan, YL Lee, FJ Hsieh and KH Lin. NKAP expression inversely correlates with NITCH1 expression and predicts favorable outcomes in Neuroblastoma. Pediatric Blood & Cancer. 55(5): P889. 2010.
                62. CJ Shih, YC Lin, YL Huang, CL Chang, WP Huang and H Lee. Sphingosine 1-phosphate-induced autophagy is mediated through activating endoplasmic reticulum stress response in human prostate cancer PC-3 cells. At 2010 The Leading Graduate School International Conference, Tsukuba, Japan. 2010.
                63. LC Hsiung, CH Wang, CL Chiang, CT Kuo, YH 
Huang, H Lee, and AM Wo. A cellular microarray perfusion system for chem-drug screenings,” Proceedings of 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Groningen, The Netherlands, October 3-7, 2010. (MicroTAS 2010)
                64. RT Lin, YS Chiang, GH Lin, H Lee and HW Liou. In vitro photothermal destruction of cancer cells using gold nanorods and pulsed-train near-infrared laser. SPIE Proceding 2011, Colloidal Quantum Dots/Nanocrystals for Biomedical Applications VI. 2011.
                65. CE Lin, JJ Lin, CH Chang, CL Chiang and H Lee. LPA-autotaxin axis enhances VEGF-C expression in human prostate cancer. FASEB 2011: 243.1, P69. 2011.
                66. CL Chiang, CL Yao, CE Lin, CH Chang and H Lee. LPA induces erythropoiesis process through activating LPA receptor 3. FASEB 2011: 1043.4, P355. 2011.
                67. CH Chang, CH Lin, CE Lin, CL Chiang and H Lee. S1P induces lymphangiogenesis through a MMP2/FGFR1-dependent pathway in human umbilical cord vein endothelial cells. FASEB 2011: 1091.3, P377. 2011.
                68. PY Wu, WM Hsu, H Lee. Aromatic Hydrocarbon Receptor Down-regulates MYCN Expression and Predicts Favorable Clinical Outcome of Neuroblastoma. ASCB2011, 63:713, 2011.
                69. YC Lin, CE Lin, YL Huang and H Lee. The study of androgen effect on LPA-induced VEGF-C expression in prostate cancer cell lines. ASCB2011, Denver, Colorado, USA, 2011.
                70. YN Lin, MSY Kao, H Lee. The investigation of LPA4 in zebrafish. The Leading Graduate School International Conference. Tsukuba, Japan, Nov. 2011.
                71. YC Lin and H Lee. The study of androgen effect on LPA-induced VEGF-C expression in prostate cancer cell lines. At 2011 The 9th Kyoto U-NTU International Exchange Activity on Long-Distance Course, Kyoto, Japan (Oral presentation & Poster), 2011.
                72. YL Huang, H Lee. De-cellularized human umbilical vein as a potential scaffold for personalized vascular tissue engineering. The 9th Kyoto U-NTU International Exchange Activity on Long-Distance Course, Kyoto, Japan, 2011.
                73. YL Liou, PY Wu, KY Tzen, ST Jou, MY Lu, YL Yang, HH Chang, DT Lin, KH Lin, WM Hsu and H Lee. Neuroblastic tumors demonstrating stronger 18F-FDOPA avidity on positron emission tomography have higher level of aromatic amino acid decarboxylase gene expression. Pediatric Blood & Cancer. 57(5): P782. 2011.
                74. CT Kuo, CL Chiang. RY Huang, H Lee, and AM Wo, Probing the traits of epithelial-mesenchymal transition in a microfluidic device,” Proceedings of 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Seattle, USA, October 2-6, 2011. (MicroTAS 2011)
                75. YC Lu, CC Chang, H Lee. Changes in tumor growth and metastatic capacities of J82 human bladder cancer cells suppressed by down-regulation of calreticulin expression. 3rd EPS Global International Forum of Regional & Targeted Cancer Therapies, p35 (oral presentation), Shang-Hai, China, 2011.
                76. KH Lin, PY Wu, WM Hsu, YF Liao and H Lee. Calreticulin up-regulates VEGF-A and VEGF-C in SK-N-DZ and SH-SY5Y neuroblastoma cell lines. FASEB 2012: 657.5, P183. 2012. (Selected presentation by APS)
                77. YC Lin, YL Huang and H Lee. The study of androgen effects on LPA-induced ROS in different human prostate cancer cell lines. FASEB 2012: 657.11, P183. 2012.
                78. CC Lin, CE Lin, YC Lin and H Lee. Lysophosphatidic acid induces reactive oxygen species generation through protein kinase C in PC-3 prostate cancer cells. FASEB 2012: 657.13, P183. 2012.
                79. YN Lin, SY Kao and H Lee.The investigation of LPA4 functions in zebrafish. FASEB 2012: 683.6, P195 2012.
                80. YL Huang, SU Chen, J Lu and H Lee. Sphingosine 1-phosphate potentiated endothelial cell attachment on de-cellularized human umbilical vein as a scaffold for vascular tissue engineering. FASEB 2012: 905.25, P295. 2012.
                81. YF Liao, YY Shih, A Nakagawara, H Lee, HF Juan, YM Jeng, DT Lin, YG Tsay, MC Huang, WM Hsu. Calreticulin mediates nerve growth factor/TrkA-elicited neuronal differentiation. Advances in Neuroblastoma Research June 18-21, 2012, Toronto, Canada.
                82. H Lee, YL Liu, MY Lu, HH Chang, ST Jou, YL Yang, DT Lin, KH Lin, KY Tzen, WM Hsu. AADC gene expression, 18F-FDOPA uptake, and tumor differentiation in neuroblastic tumors. Advances in Neuroblastoma Research June 18-21, 2012, Toronto, Canada.
                83. WM Hsu, HH Chang, CH Chen, CH Chou, H Lee, YF Liao, MC Huang. β-1,4-galactosyltransferase III expression predicts an unfavorable prognosis in neuroblastoma and enhances malignant cell phenotypes by modifying glycosylation of β1 integrin. Advances in Neuroblastoma Research June 18-21, 2012, Toronto, Canada.
                84. WM Hsu, PY Wu, H Lee, MC Huang, JH Chuang, CC Huang, MH Tai. Toll-like receptor 3 expression as a biomarker that predicts favorable prognosis in patients with neuroblastoma. Advances in Neuroblastoma Research June 18-21, 2012, Toronto, Canada.
                85. YC Lu, CC Chang, and H Lee. Study of the roles of calreticulin in bladder cancer cell invasiveness. At The 3rdLeading Graduate School International Conference, Tsukuba, Japan. 2012. (Oral presentation)
                86. YC Lin, YL Huang, and H Lee. The study of androgen effects on LPA-induced ROS in different human prostate cancer cell lines. At The 7th Tsukuba Medical Science Research Meeting, Tsukuba, Japan. 2012. (Oral presentation & Poster)
                87. KH Lin, PY Wu, and H Lee. Calreticulin up-regulates VEGF-A and VEGF-C in neuroblastoma cell lines. At The 7th Tsukuba Medical Science Research Meeting, Tsukuba, Japan. 2012.
                88. TC Tsai, BJ Wang, and H Lee. Establishment of a cell free system to detect dioxin-like compounds. At The 7th Tsukuba Medical Science Research Meeting, Tsukuba, Japan. 2012.
                89. CC Lin, CE Lin, YC Lin, and H Lee. Lysophosphatidic acid induces reactive oxygen species generation through protein kinase C in PC-3 prostate cancer cells. At The 7th Tsukuba Medical Science Research Meeting, Tsukuba, Japan. 2012. (CC Lin received the excellent poster award)
                90. CC Lin, YC Lin and H Lee. Lysophosphatidic acid induces reactive oxygen species generation through protein kinase C in PC-3 prostate cancer cells. ASCB2012: 1646, P142, 2012.
                91. CI Chen, YC Lin, CC Chang, YM Cheng, KJ Chang, CN Chen and H Lee. Mechanism of connective tissue growth factor inhibited peritoneal metastasis in gastric cancer. ASCB2012: 2426, P191, 2012.
                92. CT Kuo, CL Chiang, CT Wu, GS Huang, RYJ Huang, H Lee, and AM Wo. Microscale culture and enrichment of cancer stem cells for drug development. Proceedings of 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Okinawa, Japan, October 28 - November 1, 2012. (MicroTAS 
2012)
                93. CC Liu, SH Shieh, H Lee and HW Yuan*. 2013. A new trend: Summer schools as means to internationalise universities and curricula. 2013 APAIE Conference, HK.
                94. CC Liu, SH Shieh, H Lee* and HW Yuan. 2013. Summer programs as likely accelerators of international student recruitment.2013 APAIE Conference, HK.
                95. CC Liu, SH Shieh, H Lee* and HW Yuan. 2013. Welcome to the global lounge: Developing a space for internationalisation on the campus. 2013 APAIE Conference, HK.
                96. KH. Lin, CL. Chiang, CL Yao and H Lee. Lysophosphatidic acid inhibits megakaryocyte differentiation in CD34+ hematopoietic stem cells. FASEB 2013: 1146.1, B509, 2013
                97. YH Ho, H Lee. The role of lysophosphatidic acid in erythropoiesis in K562 human erythroleukemia cell line. FASEB 2013: 1146.2, B510, 2013
                98. TC. Tsai, BJ. Wang and H Lee. Establishment of a cell-free bioassay for detecting dioxin-like compounds. FASEB 2013: 729.1, B616, 2013
                99. CC. Lin, CE. Lin, YC. Lin and H Lee. Lysophosphatidic acid induces reactive oxygen species generation through PLC/PKC/Nox pathway in PC-3 prostate cancer cells. FASEB 2013: 1144.5, B497, 2013
                100. S-H. Lin and H. Lee. The roles of LPA2 on erythrocyte and thrombocyte differentiation in zebrafish. FASEB 2013: LB715, 2013
                101. MW. Li, CJ Huang and H. Lee. Study of the roles of LPA3 on erythropoiesis and thrombocytopoiesis processes in zebrafish. FASEB 2013: LB714, EB2013
                102. YC Lin, P-Y. Wu, SY. Lan, YL. Huang and H Lee. Aryl Hydrocarbon receptor inhibits lysophosphatidic acid-induced vascular endothelial growth factors expression in prostate cancer cells. FASEB 2013: LB716, 2013
                103. YC Lin, PY Wu, SY Lan, YL Huang, H Lee. Aryl Hydrocarbon Receptor Inhibits Lysophosphatidic Acid-Induced Vascular Endothelial Growth Factor-C Expression in Prostate Cancer Cells. The 11th NTU –Kyoto U Symposium on Molecular and Cell Biology, Kyoto, Japan, 2013. (Oral presentation)
                104. KH Lin, CL Chiang, CL Yao and H Lee. Lysophosphatidic acid inhibits megakaryocyte differentiation in CD34+ hematopoietic stem cells. FASEB SRC Lysophospholipids and other related mediators: From Bench to Clinic, Niseko, Japan, 2013
                105. YN Lin, SY Kao, BE Chang and H. Lee. The investigation of LPA4 functions in zebrafish. FASEB SRC Lysophospholipids and other related mediators: From Bench to Clinic, Niseko, Japan, 2013. (Oral presentation)
                106. H Lee. Lysophosphatidic acid as regulator for blood cell differentiation. FASEB SRC Lysophospholipids and other related mediators: From Bench to Clinic, Niseko, Japan, 2013
                107. CC Liu, SH Shieh, H Lee and HW Yuan*. 2013. Where would I like to go when studying abroad: Preferred destinations among East Asian students? 2013 EAIE Conference, Istanbul, Turkey.
                108. CC Liu, SH Shieh, H Lee and HW Yuan*. 2013. The uneven path to a joint degree: how to correctly pave the way- NTU case study. 2013 EAIE Conference, Istanbul, Turkey.
                109. CC Lin and H Lee. High glucose treatment enhanced autotaxin and VEGF-C expression in PC-3 human prostate cancer cell. ASCB2013. New Orleans, USA.
                110. KH Lin, YN Lin, YH Ho, MW Li, CL Chiang, CL Yao, and H Lee. Roles of LPA receptors in erythropoiesis. The 12th NTU-Japan International Student Mini-Symposium on Life Sciences, p17, Taipei, Taiwan, 2013. (Oral)
                111. PY Wu, WM Hsu, HF Juan, and H Lee. Aromatic hydrocarbon receptor downregulates MYCN expression and predicts favorable clinical outcome of neuroblastoma. The 12th NTU-Japan International Student Mini-Symposium on Life Sciences, p19, Taipei, Taiwan, 2013. (Oral)
                112. HY Hsia, YC Lu, and H Lee. Fucosylation modification activates β1-integrin in J82 cells. The 12th NTU-Japan International Student Mini-Symposium on Life Sciences, p31, Taipei, Taiwan, 2013.
                113. MW Li, CJ Huang, and H Lee. Investigation of the roles of LPA3 on erythropoiesis processes in vivo. The 12th NTU-Japan International Student Mini-Symposium on Life Sciences, p35, Taipei, Taiwan, 2013.
                114. YJ Yang, KH Lin, CL Chiang, CL Yao and H Lee. Lysophosphatidic acid inhibits megakaryocyte differentiation in CD34+ hematopoietic stem cells. The 12th NTU-Japan International Student Mini-Symposium on Life Sciences, p40, Taipei, Taiwan, 2013.
                115. CC Lin and H Lee. High glucose treatment enhances autotaxin and VEGF-C expression in PC-3 human prostate cancer cell. The 12th NTU-Japan International Student Mini-Symposium on Life Sciences, p41, Taipei, Taiwan, 2013.
                116. SH Lin and H Lee. The roles of LPA2 on erythrocyte differentiation in zebrafish. The 12th NTU-Japan International Student Mini-Symposium on Life Sciences, p53, Taipei, Taiwan, 2013.
                117. WM Chen and H Lee. Effects of S1P on endothelial cell reattachment on de-cellularized HUV Scaffold for vascular tissue engineering. The 12th NTU-Japan International Student Mini-Symposium on Life Sciences, p58, Taipei, Taiwan, 2013.
                118. TC Tsai, BJ Wang, and H Lee. Establishment of an aryl hydrocarbon receptor-heat shock protein 90 pull-down system to detect dioxin and dioxin-like compounds. The 12th NTU-Japan International Student Mini-Symposium on Life Sciences, p60, Taipei, Taiwan, 2013.
                119. KY Lu and H Lee. Lysophosphatidic acid upregulates calreticulin expression in PC-3 human prostate cancer cells. The 12th NTU-Japan International Student Mini-Symposium on Life Sciences, p66, Taipei, Taiwan, 2013.
                120. C-C. Lin and H Lee. High glucose treatment enhances autotaxin and VEGF-C expression in PC-3 human prostate cancer cell. FASEB 2014: 693.20, A347, San Diego, USA, 2014.
                121. W-M. Chen, H Lee, J-H. Lu and C-L. Yao. Effects of S1P on endothelial cell reattachment on de-cellularized HUV scaffold for vascular tissue engineering. FASEB 2014: 867.13, A168, San Diego, USA, 2014.
                122. Y-H. Ho, K-H. Lin, Y-N. Lin, M-W. Li, S-H. Lin, Y-J. Yang, C-L. Chiang, C-L. Yao and H Lee. LPA receptor 2 and 3 reversely regulate TPA-induced megakaryopoiesis in K562 leukemia cell line. FASEB 2014: 1094.3, A293, San Diego, USA, 2014.
                123. H Lee, C-C. Chang, C-I Chen and C-N Chen. Non-invasive ultrasound in the study of recombinant CTGF-CT therapy in mice gastric cancer model. FASEB 2014: LB497, San Diego, USA, 2014.
                124. KH Lin, PY Wu, YF Liao, WM Hsu and H Lee. Calreticulin up-regulates VEGF-A and VEGF-C in neuroblastoma cell lines. Advance in Neuroblastoma Research: POB34, 2014, Cologne, Germany.
                125. PY Wu, WM Hsu and H Lee. Aryl Hydrocarbon receptor suppresses tumor progression of neuroblastoma. Advance in Neuroblastoma Research: POB46, 2014, Cologne, Germany.
                126. YL Liu, CN Chen, IS Yu, CH Li, MY Lu, KY Tzen, H Lee, PY Wu, KH Lin, DT Lin, WM Hsu and YF Liao. Ultrasound evaluation of tumor latency and disease progression in the hemizygous TH-MYCN transgenic mice. Advance in Neuroblastoma Research: POB 108, 2014, Cologne, Germany.
                127. WM Chen, YC Lin, KH Lin, CC Lin, PY Wu and H Lee. Study of the effects of lysophosphatidic acid on lymphatic metastasis of prostate cancer. ASCB 2014: B425, P17, Philadelphia, USA.
                128. KY Lu, KH Lin, CC Lin, YC Lin, YJ Yang, WM Chen, HY Hsia and H Lee. Lysophosphatidic acid up-regulates calreticulin expression in PC-3 human prostate cancer cell. FASEB 2015: 974.2, Boston, USA, 2015. (Oral presentation)
                129. KH Lin, WC Weng, PY Wu, YC Lu, BJ Wang, YF Liao, WM Hsu and H Lee. Calreticulin up-regulates VEGFs expression in neuroblastoma cell lines. FASEB 2015: 974.7, Boston, USA, 2015.
                130. YJ Yang, CC Lin, KY Lu, WM Chen, YC Lin, CC Chang and H Lee. High glucose induces aerobic glycolysis and vascular endothelial growth factor-C through LPA signaling in human prostate cancer PC-3 cells. FASEB 2015: 977.5, Boston, USA, 2015.
                131. WM Chen, K Hsia, CL Yao, JH Lu and H Lee. S1P potentiated endothelial cell attachment on de-cellularized human umbilical vein as a scaffold for vascular tissue. At Tsukuba Global Science Week 2015, O6-P205, Tsukuba, Japan, Sep 2015. (Excellent Oral Presentation Award)
                132. JC Chiang and H Lee. The Roles of LPA Receptors During Erythropoiesis/Megakaryopoiesis in mice. At Tsukuba Global Science Week 2015, P-7. Tsukuba, Japan. Sep 2015. (Excellent Poster Presentation Award)
                133. PY Wu, YF Liao, WM Hsu and H Lee. Aryl hydrocarbon receptor suppresses tumor progression of neuroblastoma. Asia Pacific Symposium of Neuroblastoma 2015, P14-P49. Taipei, Taiwan, 2015. (Excellent Poster Presentation Award)
                134. Y Weng, K Lu and H Lee. Knockdown of calreticulin suppresses fucosylation of beta 1 integrin and cell adhesion in PC3 prostate cancer cell. ASCB 2015: P1094, P56, San Diego, USA.
                135. JC Chiang, KH Lin, YS Lin, YS Ho, CL Yao and H Lee. Pharmacological activation of LPA receptors regulates erythro-megakaryocytic differentiation in myeloid lineage. FASEB 2016: 748.3, San Diego, USA, 2016.
                136. KH Lin, WC Weng, YH Ho, PY Wu, BJ Wang, YF Liao, WM Hsu and H Lee. Calreticulin-dependent VEGF expression promote neuroblastoma differentiation. FASEB 2016: 1127.2, San Diego, USA, 2016.
                137. YC Weng, YC Chien, KY Lu and H Lee. Effects of calreticulin on FUT-1 expression and beta 1 integrin fucosylation in different cancer cells. FASEB 2016: 1127.5, San Diego, USA, 2016.
                138. WM Chen, K Hsia, CL Yao, JH Lu and H Lee. Sphingosine 1-phosphate potentiated endothelial cell attachment on decellularized human umbilical cord vein as a scaffold for vascular tissue
              • 139. CT Kuo, JY Wang, AM. Wo, BPC Chen, and H Lee, “A novel round bottom µ-well array chip with biomimetic nano-cilia promotes 3D tumor cultures and metastatic bioassays,“ Proceedings of 19th International Conference on Solid-State Sensors, Actuators and Microsystems, Kaohsiung, Taiwan, June 18-22, 2017. (Transducers 2017) (Oral Presentation)
              • 140. JC Chiang, WM Chen, KH Lin, and H Lee. Pharmacological activation of LPA receptors regulates murine erythro-megakaryocytic differentiation in myeloid lineage. ASCB 2017: B860, P2703, Philadelphia, USA.
              • 141. WM Chen and H Lee. To investigate the roles of lysophosphatidic acid type 2 receptor in cell senescence. ASCB 2017: B596, P2446, Philadelphia, USA.
              • 142. PY Chuang, YY Chan, PY Wu, PJ Chen and H Lee. Investigation of the roles of novel endogenous ligand of aryl hydrocarbon receptor in neural development. ASCB 2017: B527, P3240, Philadelphia, USA.
              • 143. PY Chuang, YY Chan, PY Wu, PJ Chen and H Lee. Investigation of the roles of novel endogenous ligand of aryl hydrocarbon receptor in neural development. EB 2018: 864.19, San Diego, USA, 2018.
              • 144. CY Chen, YC Chien and H Lee. Calreticulin stabilizes vascular endothelial growth factor-A mRNA via interaction with AU-rich element at 3’-UTR. EB 2018: 614.2, San Diego, USA, 2018.
              • 145. WM Chen, YC Chang, YN Lin, JC Chiang, H Lee. Histological Analysis of Lysophosphatidic Acid Receptor 3 Deficient Zebrafish. EB 2019: 705.5, Orlando, USA, 2019.
              • 146. JC Chiang, KH Lin, WM Chen, H Lee. Lysophosphatidic Acid Regulates Erythropoiesis at Different Hematopoietic Hierarchy. EB 2019: 705.4, Orlando, USA, 2019.

           

          Book Chapters

          1. EJ Goetzl, S An, H Lee. Lysophospholipid growth factor receptors. Cytokine Reference, Online chapter. Academic Press, 2000.

          • 2. EJ Goetzl, H Lee, GTigyi. Lysophospholipid growth factors. Cytokine Reference, Online chapter. Academic Press, 2000.
          • 3. YF Liao, WM Hsu, H Lee, MK Hu, HF Juan, MC Huang, HH Chang,  BJ Wang, YY Shihand YG Tsay(2012). Molecular Chaperones as Prognostic Markers of Neuroblastoma, Neuroblastoma - Present and Future, Hiroyuki Shimada (Ed.), ISBN: 978-953-307-016-2, InTech, Available from: http://www.intechopen.com/articles/show/title/molecular-chaperones-as-prognostic-markers-of-neuroblastoma

          Conference Pesentation

            • 1. H Lee, EJ Goetzl, S An. Effects of lysophosphatidic acid and sphingosine 1-phosphate on endothelial cells. FASEB Meeting, Washington D.C. April, 1999.
            • 2. H Lee, EJ Goetzl.  Effects of LPLs on macrophage functions.  At FESEB Summer Research Conference: Lysophospholipids and Related Bioactive Lipids in Biology and Diseases. Tucson, Arizona. June 2001.
            • 3. H Lee.Effects of LPLs on cardiovascular system. At 2005 Biomedical annual meeting of Taiwan.  Taipei. April 2005.
            • 4. H Lee. Effects of LPLs on endothelial cell functions. At 2005 AEARU meeting, Beijing, China. September 2005.
            • 5. H Lee.An introduction for angiogenic basic research and endothelial cell as a model system. At 2006 Annual Meeting and Scientific Congress of Angiogenesis, Taipei, Taiwan.
            • 6. H Lee.Lysophospholipids are regulators of lymphangiogenesis. At 2007 Asian Chapter Congress of the International Union of Angiology, Taipei, Taiwan
            • 7. H Lee.Lysophospholipids are regulators of lymphangiogenesis. At 2008 Symposium of Angiogenesis in Cancer Therapy at NTUH, Taipei, Taiwan
            • 8. H Lee.Lysophosphatidic acid is regulator for lymphangiogenesis. At 2008 NHRI Vascular Biology Conference at NHRI, Hsingchu, Taiwan
            • 9. H Lee.Lysophospholipids are regulators of lymphangiogenesis. At 2010 International Symposium on tumor microenvironment interaction at Mackay Hospital, Taipei, Taiwan
            • 10. H Lee.LPA Induces the Erythropoiesis Process through Activating LPA Receptor 3. At the 9th Kyoto U-NTU Symposium on Molecular and Cellular Biology.  June 2011, Kyoto, Japan.
            • 11. H Lee.Lysophospholipids as lymphangiogenesis regulators. At the 22nd Pacific Science Congress Meeting. 14-17 June 2011, Kuala Lumpur, Malaysia.
            • 12. H Lee.The physiological functions of lysophosphatidic acid. At the 10th Japan-NTU Symposium on Molecular and Cellular Biology.  Jan. 8th, 2012, Taipei, Taiwan.
            • 13. H Lee.NTU English taught programs: Challenges and Opportunities. At the NAFSA2012, June 1st, 2012, Houston, USA.
            • 14. H Lee.The roles of calreticulin in bladder cancer cell invasiveness. Center for Comparative Respiratory Biology and Medicine (CCRBM)Seminar, UC Davis. June 22nd, 2012, Davis, USA.
            • 15. H Lee.The roles of calreticulin in bladder cancer cell invasiveness. TLSA of UK September 2nd, 2012, Oxford, UK.
            • 16. H Lee. The roles of calreticulin in bladder cancer cell invasiveness. Oct. 29th, 2012, at the School of Medicine, University of Nagoya, Nagoya, Japan.
            • 17. H Lee. The roles of calreticulin in bladder cancer cell invasiveness. Nov. 1st, 2012 at the Leading Graduate Schools International Conference 2012, Tsukuba, Japan.
            • 18. H Lee.APAIE 2013 Parallel Sessions: A New Trend: Summer Schools as Means to Internationalize Universities and Curricula. March. 13th, 2013 at APAIE 2013, Hong Kong.
            • 19. H Lee.APAIE 2013 Parallel Sessions: Welcome to the Global Lounge: Developing a space for internalization on the campus. March. 12th, 2013 at APAIE 2013, Hong Kong.
            • 20. H Lee.  LPA induces the erythropoiesis process through activating LPA receptor 3. Department of Physiology Continuing Series of Seminar, University of Tennessee. April 18th, 2013, Memphis, USA.
            • 21. H Lee. Investigation of the Physiological Functions of Lysophosphatidic Acid (LPA)
              on Hemopoietic Lineage. Institute of Oral Biology Seminar Series, National Taiwan University. May 13th, 2013, Taipei, Taiwan.
            • 22. H Lee. The roles of calreticulin in bladder cancer cell invasiveness. July 30th, 2013 at the Human Biology Seminar of Tsukuba University, Tsukuba, Japan.
            • 23. H Lee. Lysophosphatidic acid as regulator for blood cell differentiation.  At FASEB Scientific Research Conference: Lysophospholipids and Related Bioactive Lipids in Biology and Diseases. August 6th, 2013, Niseko, Japan.
            • 24. H Lee.  Investigation of the roles of lysophospholipids on prostate cancer. Monthly Meeting of Prostate Cancer Working Group, University of Texas Southwestern. Nov 13th, 2013, Dallas, USA.
            • 25. H Lee.  Investigation of the roles of lysophospholipids on prostate cancer. Dec 12nd, 2013, Stower Institute, Kansas City, USA.
            • 26. H Lee. Lysophosphatidic acid as regulator for blood cell differentiation. At the Second Joint Symposium of NTU-Kyoto U. Sep 1st, 2014, Kyoto, Japan.
            • 27. H Lee. Lysophosphatidic acid as regulator for blood cell differentiation. At 1007th Biological Science Seminar, Department of Biological Science, University of Tokyo, Sep 4th, 2014, Tokyo, Japan.
            • 28. H Lee. Lysophosphatidic acid as regulator for blood cell differentiation. Development Center for Biotechnology of Taiwan, Nov  28th, 2014, Taipei, Taiwan.
            • 29. H Lee. Lysophosphatidic acid as regulator for blood cell differentiation. NIG-NTU Symposium, March 20th, 2015, Taipei, Taiwan.
            • 30. H Lee. Lysophosphatidic acid as regulator for blood cell differentiation. Biopharmaceutical Departmental Seminar, Yang Ming University, April 30th, 2015, Taipei, Taiwan.
            • 31. H Lee.  Lysophosphatidic acid as regulator for blood cell differentiation. SBCA, June 28th, 2015, Taipei, Taiwan.
            • 32. H Lee. The roles of calreticulin in bladder cancer cell invasiveness. Aug 7th, 2015 at Departmental Seminar of Shuang Ho Hospital, New Taipei City, Taiwan.
            • 33. H Lee. The roles of calreticulin in bladder cancer cell invasiveness. Oct 1st, 2015 at the Human Biology Seminar of Tsukuba University, Tsukuba, Japan.
            • 34. H Lee. The roles of calreticulin in bladder cancer cell invasiveness. Dec 10th, 2015 at the NTU-University of Tokyo Biological Science Seminar 2015, Tokyo, Japan.
              • 35 .H Lee.  Lysophosphatidic acid as regulator for blood cell differentiation. Institute of Biotechnology, Yuanchi University, May 11th, 2016, Chungli, Taiwan.
              • 36 .H Lee. Lysophosphatidic acid as a target of personalized medicine for prostate cancer progression. UTSW Dragon Gate retreat, University of Texas Southwestern, July 3rd, 2016, Dallas, USA
              • 37. H Lee. Lysophosphatidic acid as a target of personalized medicine for prostate cancer progression. Mcmicken College of Arts and Sciences, University of Cincinnati, July 14th, 2016, Cincinnati, USA.
              • 38. H Lee, Taiwanese Academic Panel Discussion: R&D environment for Taiwan Bioscience. BTBA Symposium, July 17th, 2016, Boston, USA.
              • 39. H Lee. Lysophosphatidic acid as a target of personalized medicine for prostate cancer progression. Department of Mechanical Engineering, Johns Hopkins University, July 20th, 2016, Baltimore, USA
              • 40. H Lee. Lysophosphatidic acid as a target of personalized medicine for prostate cancer progression. School of Biological Science and Technology, Jinan University, Dec 14th, 2016, Jinan, China.
              • 41.H Lee. ParaStamp and its application to cell patterning, drug synergy screening and rewritable devices for droplet storage. Bordeaux –Kyoto Symposium, June 29th, 2017, Bordeaux, France.
            • 42. H Lee. The roles of endogenous ligand for AHR in neural development and tumorigenesis of neuroblastoma. The 3rd Asia Pacific International Symposium of Neuroblastoma, October 6th, 2017, Tokyo, Japan. (as Keynote Speaker)
            • 43. H Lee. ParaStamp and its application to cell patterning, drug synergy screening and rewritable devices for droplet storage. Texas Taiwanese Biotechnology Association Symposium, Nov 3rd, 2017, Dallas, USA.
            • 44. H Lee. Lysophosphatidic acid as a target of personalized medicine for prostate cancer progression. School of Life Science, Sun Yat-Sen University, Dec 7th, 2016, Guangzhou, China
            • 45. H Lee. Lysophosphatidic acid as a target of personalized medicine for prostate cancer progression. School of Biomedicine, Jinan University, Dec 8th, 2016, Guangzhou, China
            • 46. H Lee. Lysophosphatidic acid as a target of personalized medicine for prostate cancer progression. Biology Summer Camp, June 27th, 2018, Kinman, Taiwan
            • 47. H Lee. Biology of Lysophospholipids in prostate cancer. At the 17th International Joint Symposium on Molecular and Cellular Biology, Kyoto University, June 29th, 2018, Kyoto, Japan (as Keynote Speaker)

             

            References

            Dr. Richard I. Weiner
            Professor
            Department of Physiology and Ob/Gyn
            University of California, San Francisco
            3rd and Parnassus
            San Francisco, CA94143-0556

            Dr. Songzhu An
            Assistant Professor
            Department of Medicine
            Division of Immunology and Allergy
            University of California, San Francisco
            3rd and Parnassus
            San Francisco, CA94143-0711

            Dr. Edward J. Goetzl
            Professor
            Department of Medicine
            University of California, San Francisco
            3rd and Parnassus
            San Francisco, CA94143-0711
     
     
     
     
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